Predictive Data.
Fewer Re-runs
Make faster go/no-go calls in lead-opt and IND-enabling with consistent, transporter-aware metabolism data, reducing CRO repeats and conflicting Clint rankings. Our assay-ready kits drop into your workflow in either 96-well plates or single-use vials for true plug-and-play adoption.
Lot-to-Lot Reproducibility
Fixed CPR:CYP ratios in defined membranes keep CVs tight.
Transporter-Aware Metabolism
Optional P-gp/OATP combos capture permeability-metabolism interplay.
Assay-Ready Format
Lyophilized kits with built-in NADPH regeneration, add compound, incubate, analyze.
Cleaner Spectra
Minimal background peaks vs. pooled microsomes/S9.
Our Technology
We reconstitute human CYP450s and CPR (± transporters) into a defined lipid bilayer, optimize orientation and stoichiometry, and stabilize the system for shelf-life and reproducibility.
Inside:
-
CYP + CPR with tuned ratios for isoform-accurate kinetics
-
NADPH regeneration
-
Optional UGT/transferase add-ons for Phase I→II workflows
Membrane engineering:
-
Lipid compositions that maximize turnover and stability
-
Porin-tuned flux for cofactors and small molecules
What Our Partners Are Saying
״Being able to toggle transporter activity in the same system finally let us see the DDI we expected.״
John Nelson, Toxicology in vitro
״Reproducibility was the difference. The kits gave us the same rank-order we saw in human data without the variability we encounter with microsomes.״
Molecular Pharmacologist
״We have been thoroughly impressed with Fermenta Bioworks' platform. Their biological manufacturing advancements have provided us with a more sustainable approach to drug production, and their collaborative partnerships have been instrumental in driving positive change in the industry.״
Sophia Rodriguez, Research Scientist
